GPVI Antibody


Western Blot: GPVI Antibody [NBP1-76941] - Analysis in K562 cell lysate with antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: GPVI Antibody [NBP1-76941] - Human Heart cells.
Immunohistochemistry-Paraffin: GPVI Antibody [NBP1-76941] - Human heart tissue with Glycoprotein VI antibody at 10 ug/ml.
Western Blot: GPVI Antibody [NBP1-76941] - A20 lysate with GPVI antibody at 1ug/mL in either the absence or (B) the presence of blocking peptide.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
1 mg/ml

Order Details

GPVI Antibody Summary

Antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human GPVI.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
68 kDa
Control Peptide
GPVI Peptide (NBP1-76941PEP)

Alternate Names for GPVI Antibody

  • Glycoprotein 6
  • glycoprotein VI (platelet)
  • GP6
  • GPIV
  • GPVIplatelet collagen receptor
  • MGC138168
  • platelet glycoprotein VI


Glycoprotein VI (GP6) is a 58kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. It is uniquely expressed by cells of the megakaryocytic/platelet lineage, and is a member of the immunoglobulin gene superfamily, closely related to Fc receptor gamma chain (FcRgamma) and natural killer receptors. Glycoprotein VI plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcRgamma, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2. GPVI deficiency can result in bleeding disorders. Further study should reveal the extent of GPVI involvement in thrombotic disease and allow the development of alternative anti-thrombotic compounds.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol GP6

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