GPR68 Antibody

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Immunohistochemistry-Paraffin: GPR68 Antibody [NLS1195] - Analysis of anti-GPR68 antibody with human brain, cortex.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Eq, Ha, Mk, PmSpecies Glossary
Applications ELISA, IHC-P, ICC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

GPR68 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from C-terminus of human GPR68.
Specificity
Human GPR68. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (95%), Rat (95%), Hamster (95%), Monkey (100%), Equine (95%), Primate (95%), Bovine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPR68
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 5 - 7.5 ug/ml
  • Immunocytochemistry 1:10 - 1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmost (95%), Elephant (95%), Rabbit (85%), Porcine (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GPR68 Antibody

  • G protein-coupled receptor 68
  • GPR12A
  • G-protein coupled receptor 68
  • MGC111379
  • OGR-1
  • OGR1MGC156983
  • ovarian cancer G protein-coupled receptor, 1
  • ovarian cancer G-protein coupled receptor 1
  • Sphingosylphosphorylcholine receptor

Background

OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003). OGR1 has been reported to be expressed in blood, brain, heart, kidney, lung, placenta, small intestine, spleen, and testis. ESTs have been isolated from blood, lung, and uterine libraries. Caution: OGR1 is also known as GPR12A, which is distinct from GPR12 in cluster 3851.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GPR68
Entrez