gp130/CD130 Antibody (KGP130)


Flow Cytometry: CD130 Antibody (KGP130) [NBP2-00335] - Staining of BALB/c splenocytes with Anti-Mouse CD3e FITC and 0.125 ug of Rat IgG2a kappa Isotype Control Purified (left) or 0.125 ug of Anti-Mouse CD130 Purified more

Product Details

Reactivity MuSpecies Glossary
Applications WB, Flow
0.5 mg/ml

gp130/CD130 Antibody (KGP130) Summary

The immunogen for this antibody is CD130.
Preincubation of mouse splenic T cells with IL-6 is capable of blocking the interaction of KGP130 with gp130, suggesting that the KGP130 binding site lies near the IL-6 interaction domain. Reactivity of KGP130 towards human gp130 has not been observed.
IgG2a Kappa
Protein A or G purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Aqueous buffer, may contain carrier protein/stabilizer (proprietary).
0.09% Sodium Azide
0.5 mg/ml
Protein A or G purified

Reactivity Notes


Alternate Names for gp130/CD130 Antibody (KGP130)

  • CD130 antigen
  • CD130
  • CDw130
  • DKFZp564F053
  • gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
  • GP130
  • IL-6 receptor subunit beta
  • IL-6R subunit beta
  • IL-6RB
  • IL-6R-beta
  • IL6ST
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • interleukin receptor beta chain
  • interleukin-6 receptor subunit beta
  • Interleukin-6 signal transducer
  • Membrane glycoprotein 130
  • membrane glycoprotein gp130
  • Oncostatin-M receptor subunit alpha


The KGP130 monoclonal antibody reacts with mouse gp130, also known as CD130. gp130 is a 130 kD Type-I transmembrane glycoprotein containing a 597 amino acid extracellular domain, a single transmembrane domain, and a 277 amino acid cytoplasmic domain. gp130 is a subunit of several heterodimeric cell-surface receptors, including receptors for IL-6, IL-11, IL-27, Oncostatin M, and Leukemia Inhibitory Factor (LIF). The gp130 protein has also been found to exist in a soluble form, which is capable of inhibiting IL-6 signaling. gp130 is expressed mainly on T cells, monocytes, endothelial cells, activated B cells, and plasma cells, and is expressed at lower levels on most leukocytes and epithelial cells. In response to ligand binding, gp130 becomes tyrosine phosphorylated, leading to activation of several signaling pathways including the PI3 kinase, Ras-MAPk and Stat pathways.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP2-00335AF405
Alexa Fluor (R) 488 Labeled NBP2-00335AF488
Alexa Fluor (R) 647 Labeled NBP2-00335AF647
Alexa Fluor (R) 700 Labeled NBP2-00335AF700
Allophycocyanin Labeled NBP2-00335APC
DyLight 350 Labeled NBP2-00335UV
DyLight 405 Labeled NBP2-00335V
DyLight 405LS Labeled NBP2-00335V3
DyLight 488 Labeled NBP2-00335G
DyLight 680 Labeled NBP2-00335FR
DyLight 755 Labeled NBP2-00335IR
PE Labeled NBP2-00335PE
PerCP Labeled NBP2-00335PCP

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Contact Information

Product PDFs


Gene Symbol IL6ST

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