GMDS Antibody (2A1)

Images

 
Western Blot: GMDS Antibody (2A1) [NBP2-03385] HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
2A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

GMDS Antibody (2A1) Summary

Immunogen
Full length human recombinant protein of human GMDS (NP_001491) produced in HEK293T cell.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GMDS
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GMDS Antibody (2A1)

  • EC 4.2.1.47
  • GDP-D-mannose dehydratase
  • GDP-mannose 4,6-dehydratase
  • GMDGDP-mannose 4,6 dehydratase
  • SDR3E1
  • short chain dehydrogenase/reductase family 3E, member 1

Background

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GMDS
Entrez