Recombinant Human GM-CSF Protein Summary
A partial protein corresponding to CSF2.
E. coli expressed amino acids ala 18 - glu144 of mature human GMCSF (accession # NM_000758).
|Details of Functionality
This recombinant human GM-CSF has been tested in bioassays using human TF-1 cell line. The ED50 measured in a TF-1 proliferation assay is typically 100 pg/ml, corresponding to a specific activity of approximately 1.0 x10^7Units/mg.
| Protein/Peptide Type
Partial Recombinant Protein
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
This protein was made to the human sequence.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid; phosphate buffered saline, pH 7.2, 150 mM NaCl, with 1.0% BSA. 0.22um filtered.
0.09% Sodium Azide
Alternate Names for Recombinant Human GM-CSF Protein
- colony stimulating factor 2 (granulocyte-macrophage)
- Colony-stimulating factor
- GMCSFgranulocyte-macrophage colony-stimulating factor
- granulocyte-macrophage colony stimulating factor
Human GM-CSF (Granulocyte/Monocyte-Colony Stimulating Factor) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-alpha, IL-1, IL-2 and IFN-gamma. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their progenitors.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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