Glucagon R/GCGR Antibody

Images

 
Western Blot: Glucagon R/GCGR Antibody [NBP1-00850] - Analysis of Glucagon Receptor (K136) pAb at 1:1000 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:SP2/0 whole cell ...read more
Western Blot: Glucagon R/GCGR Antibody [NBP1-00850] - Western blot (WB) analysis of Glucagon Receptor (K136) antibody in extracts from COLO205 cells
Western Blot: Glucagon R/GCGR Antibody [NBP1-00850] - Extracts from PC12 cells.
Western Blot: Glucagon R/GCGR Antibody [NBP1-00850] - Lane1:HEK293T whole cell lysate. Lane2: Raw264.7 whole cell lysate. Lane3: H9C2 whole cell lysate.

Product Details

Summary
Product Discontinued
View other related Glucagon R/GCGR Primary Antibodies

Order Details


    • Catalog Number
      NBP1-00850
    • Availability
      Product Discontinued

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Glucagon R/GCGR Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 100-150 of Human Glucagon Receptor.
Specificity
Glucagon Receptor (K136) detects endogenous levels of Glucagon Receptor protein.
Clonality
Polyclonal
Host
Rabbit
Gene
GCGR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
Application Notes
Immunohistochemistry on frozen sections reported in scientific literature (PMID: 19897672).
Theoretical MW
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-00850 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Glucagon R/GCGR Antibody

  • FLJ97182
  • GCGR
  • GGR
  • GLR
  • GL-R
  • Glucagon R
  • glucagon receptor
  • GlucagonR
  • MGC138246

Background

Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The 56 GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Glucagon R/GCGR Antibody (NBP1-00850)(2)

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 2 applications: IHC-Fr, WB.


Filter By Application
IHC-Fr
(1)
WB
(1)
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Filter By Species
Human
(1)
Rat
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Diseases for Glucagon R/GCGR Antibody (NBP1-00850)

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Bioinformatics

Gene Symbol GCGR
Entrez
Uniprot