GITR/TNFRSF18 Antibody (YGITR 765)



Product Details

Product Discontinued
View other related GITR/TNFRSF18 Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

GITR/TNFRSF18 Antibody (YGITR 765) Summary

This antibody was generated by immunizing host with Recombinant mouse GITR protein and Transfected cells
Low levels on resting T cells, high on CD4+CD25+ Treg cells, expression upregulated upon activation.
IgG2b Kappa
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Phosphate-buffered solution, pH 7.2,
0.09% Sodium Azide
0.5 mg/ml
Protein A or G purified


Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.


GITR, Glucocorticoid-induced TNFR-related gene, is a member of the TNF receptor superfamily, also known as TNFRSF18, and AITR (in humans). It is expressed at low levels on resting T lymphocytes and at high levels on CD4+CD25+ T regulatory (Treg) cells. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-kappaB activation, and abrogate the inhibitory functions of CD4+CD25+ Treg cells. In vivo activation GITR causes development of autoimmune diseases and restores the suppressed immune responses.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu
Applications: Flow, IHC, ICC
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Species: Hu
Applications: Flow, Func, In vitro, In vivo, Flow-CS
Species: Hu
Applications: WB, Flow, AgAct
Species: Hu
Applications: WB, Flow, Func, IHC, IHC-Fr, IP
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
Applications: Func-Inh

Publications for GITR/TNFRSF18 Antibody (NBP1-48663) (0)

There are no publications for GITR/TNFRSF18 Antibody (NBP1-48663).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for GITR/TNFRSF18 Antibody (NBP1-48663) (0)

There are no reviews for GITR/TNFRSF18 Antibody (NBP1-48663). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

FAQs for GITR/TNFRSF18 Antibody (NBP1-48663) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional GITR/TNFRSF18 Antibody (YGITR 765) Products

Related Products by Gene

Bioinformatics Tool for GITR/TNFRSF18 Antibody (NBP1-48663)

Discover related pathways, diseases and genes to GITR/TNFRSF18 Antibody (NBP1-48663). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for GITR/TNFRSF18 Antibody (NBP1-48663)

Discover more about diseases related to GITR/TNFRSF18 Antibody (NBP1-48663).

Pathways for GITR/TNFRSF18 Antibody (NBP1-48663)

View related products by pathway.

PTMs for GITR/TNFRSF18 Antibody (NBP1-48663)

Learn more about PTMs related to GITR/TNFRSF18 Antibody (NBP1-48663).

Blogs on GITR/TNFRSF18

There are no specific blogs for GITR/TNFRSF18, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol TNFRSF18

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-48663 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.