Ghrelin/Obestatin Antibody

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Immunohistochemistry-Paraffin: Ghrelin/Obestatin Antibody [NBP1-50395] - Analysis of anti-Ghrelin antibody with human colon at concentration 2 ug/ml.
Immunohistochemistry-Paraffin: Ghrelin/Obestatin Antibody [NBP1-50395] - Analysis of anti-Ghrelin antibody with human colon at concentration 2 ug/ml.

Product Details

Summary
Reactivity Hu, Mk, Mu, HaSpecies Glossary
Applications ELISA, IHC-P
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Ghrelin/Obestatin Antibody Summary

Immunogen
Synthetic peptide C-QDILWEEAKEAPADK from the C-terminus of human GHRL / Ghrelin (NP_057446.1; NP_001128413.1; NP_001128416.1; NP_001128417.1; NP_001128418.1).
Specificity
Human GHRL / Ghrelin. This antibody is expected to recognise all reported isoforms.
Predicted Species
Mouse (93%), Hamster (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
GHRL
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1:8000
  • Immunohistochemistry-Paraffin 2 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%0, Baboon (100%), Elephant (100%), Gorilla (93%), Marmoset (87%), Rat (87%), Porcine (87%), Equine (80%).

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
TBS (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Ghrelin/Obestatin Antibody

  • appetite-regulating hormone
  • ghrelin
  • ghrelin/obestatin preprohormone
  • ghrelin/obestatin prepropeptide
  • Ghrelin/Obestatin
  • Growth hormone secretagogue
  • Growth hormone-releasing peptide
  • Motilin-related peptide
  • MTLRPgrowth hormone secretagogue receptor ligand
  • obestatin
  • Protein M46

Background

Ghrelin is an orexigenic (food intake stimulating) 27 or 28 amino-acid gut-brain peptide hormone produced by endocrine cells in the stomach, pancreatic islets and certain hypothalamic neurons1,2. Two forms are produced by alternative mRNA splicing; Gln13 or 14 is missing from the second form."Active" ghrelin is acylated (octanoylated) at Ser3; this form stimulates growth hormone secretion via GHS receptors and increases appetite. The des-acyl form does not have these effects but may have other actions. Plasma responses of total ghrelin to food reflect those of active ghrelin3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GHRL
Entrez
Uniprot