GGA1 Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-03396
    • Availability
      Product Discontinued

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GGA1 Antibody Summary

Immunogen
A synthetic peptide from the GAT domain of human GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in many other species including rat, mouse, xenopus, zebrafish.
Localization
subcellular location: golgi apparatus, trans-golgi network membrane; peripheral membrane protein. endosome membrane; peripheral membrane protein. tissue specificity: ubiquitously expressed.
Specificity
GGA1.
Clonality
Polyclonal
Host
Rabbit
Gene
GGA1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for GGA1 Antibody

  • ADP-ribosylation factor binding protein 1
  • ADP-ribosylation factor-binding protein GGA1
  • gamma adaptin ear containing, ARF binding protein 1
  • gamma-adaptin related protein 1
  • Gamma-adaptin-related protein 1
  • golgi-associated, gamma adaptin ear containing, ARF binding protein 1
  • Golgi-localized, gamma ear-containing, ARF-binding protein 1

Background

GAA1 is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network (TGN). They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. GAA1 is a ubiquitously expressed membrane-associated protein localised to the TNG and endosomes. Multiple alternatively spliced transcript variants encoding different isoforms have been found for GAA1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GGA1
Entrez
Uniprot