Recombinant GDNF Protein

Images

 

Product Details

Summary
Product Discontinued
View other related GDNF Peptides and Proteins

Order Details


    • Catalog Number
      NBP1-43175
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Recombinant GDNF Protein Summary

Description
A partial protein corresponding to GDNF.
Preparation
Method
E. coli-expressed amino acids Ser78 - Ile211 (Accession # CAG46721).
Details of Functionality
This recombinant human GDNF has been tested in bioassays by rat C6 cell proliferation. The ED50, calculated by dose-dependent induction of rat C6 cell proliferation, is 1ug/ml, corresponding to a specific activity of 1x10^4units/mg.
Protein/Peptide Type
Partial Recombinant Protein
Gene
GDNF
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Reactivity Notes

This protein was made to the human sequence.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sterile liquid, 10 mM Phosphate buffer, 150 mM NaCl with 1.0% BSA. 0.22 um filtered.
Preservative
0.09% Sodium Azide

Notes

Purity: Greater than 98%, as determined by SDS-PAGE

Alternate Names for Recombinant GDNF Protein

  • Astrocyte-derived trophic factor
  • ATF
  • ATF1
  • ATF2
  • GDNF
  • glial cell derived neurotrophic factor
  • glial cell line derived neurotrophic factor
  • glial cell line-derived neurotrophic factor
  • HFB1-GDNF
  • hGDNF
  • HSCR3

Background

Glial Cell derived Neurotrophic Factor (GDNF), a member of the TGF superfamily, is a neurotrophic factor that promotes the survival of various neuronal populations in both the central and peripheral nervous systems during their development. Neuronal subpopulations affected by GDNF include motor neurons, midbrain dopaminergic neurons and Purkinje cells. GDNF is conserved across mammalian species with human and rat orthologs sharing approximately 93% amino acid sequence identity. E. coli-produced recombinant human GDNF is a disulfide-linked, non-glycosylated homodimer composed of two 135 amino acid polypeptides.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

248-BD/CF
Species: Hu, Mu, Rt, Ca, Eq
AF482
Species: Mu
Applications: WB, IHC
AF1085
Species: Mu
Applications: WB, IHC, Neut
NBP2-37576
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC
AF477
Species: Hu, Mu
Applications: WB, IHC, Block
NB300-109
Species: Hu, Mu, Rt, Dr, I, Ma
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, IHC-FrFl
NB100-410
Species: Hu, Mu
Applications: WB, IP
NBP2-50037
Species: Hu, Mu, Rt, Po, Bv, Eq
Applications: WB, ICC/IF
557-NT/CF
Species: Rt
MAB17761
Species: Hu, Mu, Rt
Applications: WB, ICC
NB100-56530
Species: Hu
Applications: WB
MAB5526
Species: Hu, Mu
Applications: WB
NBP1-43175
Applications: IA

Publications for GDNF Protein (NBP1-43175) (0)

There are no publications for GDNF Protein (NBP1-43175).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for GDNF Protein (NBP1-43175) (0)

There are no reviews for GDNF Protein (NBP1-43175). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for GDNF Protein (NBP1-43175) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional GDNF Products

Bioinformatics Tool for GDNF Protein (NBP1-43175)

Discover related pathways, diseases and genes to GDNF Protein (NBP1-43175). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for GDNF Protein (NBP1-43175)

Discover more about diseases related to GDNF Protein (NBP1-43175).
 

Pathways for GDNF Protein (NBP1-43175)

View related products by pathway.

PTMs for GDNF Protein (NBP1-43175)

Learn more about PTMs related to GDNF Protein (NBP1-43175).
 

Research Areas for GDNF Protein (NBP1-43175)

Find related products by research area.

Blogs on GDNF.

The identification of dopaminergic neurons using Tyrosine Hydroxylase in Parkinson's research and LRRK2
Tyrosine hydroxylase (TH) is a crucial enzyme involved in the biosynthesis of dopamine, norepinephrine and epinephrine in the brain.  Specifically, TH catalyzes the conversion of l-tyrosine to l-dihydroxyphenylalanine (l-dopa).  The importance of t...  Read full blog post.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant GDNF Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol GDNF
Entrez