Recombinant Human GDF-8/Myostatin Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99233
    • Availability
      Product Discontinued

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Recombinant Human GDF-8/Myostatin Protein Summary

Description
A recombinant protein corresponding to 109 amino acids of Human GDF-8/Myostatin
Preparation
Method
>98% SDS-PAGE
Details of Functionality
Biological Activity: Determined by its ability to inhibit the proliferation of MPC-11 cells. The ED50 for this effect is <20 ng/ml.
Results: <20 ng/ml
Protein/Peptide Type
Recombinant Protein
Gene
MSTN
Purity
>90% SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and with no additives.
Concentration
Lyoph
Purity
>90% SDS-PAGE
Reconstitution Instructions
Reconstitute with sterilized 20 mM Acetic acid to a final concentration of 0.1 - 1.0 mg/ml.

Notes

After reconstituted, dilute further with other aqueous solutions.

Alternate Names for Recombinant Human GDF-8/Myostatin Protein

  • GDF8
  • GDF-8
  • GDF8growth differentiation factor 8
  • growth/differentiation factor 8
  • MSTN
  • Myostatin

Background

Myostatin, also known as Growth Differentiation Factor-8 (GDF-8), belongs to the TGF-Beta superfamily. Along with other members of the TGF-Beta family, Myostatin plays a crucial role as a regulator for embryonic development and tissue homeostasis in adult animals. Early studies show that Myostatin has the ability to halt muscle growth. New research has further suggested that Myostatin may also be involved in reducing and preventing adiposity and type-2 diabetes. Human Myostatin is a homodimeric protein with each subunit containing 109 amino acid residues with a total molecular weight of 24.8 kDa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol MSTN
Entrez