GDF-7/BMP-12 Recombinant Protein Summary
A recombinant protein corresponding to two 122 amino acids of Human GDF-7/BMP-12
Source: E. coli
Amino Acid Sequence: The amino acid sequence of this product is not available.
|Details of Functionality
The protein is biologically active as determined by its ability to induce alkaline phosphatase production by ADTC5 mouse chondrogenic cells. The EDSO for this effect is typically 0.2 2.5ug/ml.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
Sterile filtered and with no additives.
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml.
After reconstituted, dilute further with other aqueous solutions.
Alternate Names for GDF-7/BMP-12 Recombinant Protein
- growth differentiation factor 7
- growth/differentiation factor 7
BMPs (bone morphogenetic proteins) belong to the TGF-Beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. Recombinant human BMP-12 is a 27 kDa disulfide-linked homodimer containing two 122 amino acid polypeptide chains.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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