Recombinant Human GDF-5/BMP-14 Protein


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Product Details

Reactivity HuSpecies Glossary
Applications PAGE, Bioactivity

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Recombinant Human GDF-5/BMP-14 Protein Summary

Recombinant bioactive protein containing 120 amino acids for Human GDF-5/BMP-14

Source:E. coli
Amino Acid Sequence:(X80915)

Determined to be >98% pure by SDS-PAGE
Details of Functionality
The ED50 as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is 1-2 ug/ml.
E. coli
Protein/Peptide Type
Recombinant Protein
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug


Theoretical MW
27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at -20 to -80C. Avoid freeze-thaw cycles.
Sterile filtered and lyophilized from 10 mM Sodium Citrate, pH 3.5.
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute to a concentration of 0.1-1.0 mg/ml in H2O containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.

Alternate Names for Recombinant Human GDF-5/BMP-14 Protein

  • BMP14
  • BMP-14
  • Cartilage-derived morphogenetic protein 1
  • cartilage-derived morphogenetic protein-1
  • CDMP-1
  • GDF5
  • GDF-5
  • growth differentiation factor 5
  • growth/differentiation factor 5
  • OS5
  • radotermin
  • SYNS2


BMPs (bone morphogenetic proteins) belong to the TGF-Beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development. Recombinant human BMP-14 is a 27 kDa homodimeric protein consisting of two 120 amino acid polypeptide chains.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Gene Symbol GDF5