Recombinant Human GDF-5/BMP-14 Protein Summary
Recombinant bioactive protein containing 120 amino acids for Human GDF-5/BMP-14
Amino Acid Sequence:(X80915)
Determined to be >98% pure by SDS-PAGE
|Details of Functionality
The ED50 as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is 1-2 ug/ml.
| Protein/Peptide Type
>95%, by SDS-PAGE
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at -20 to -80C. Avoid freeze-thaw cycles.
Sterile filtered and lyophilized from 10 mM Sodium Citrate, pH 3.5.
>95%, by SDS-PAGE
Reconstitute to a concentration of 0.1-1.0 mg/ml in H2O containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.
Alternate Names for Recombinant Human GDF-5/BMP-14 Protein
- Cartilage-derived morphogenetic protein 1
- cartilage-derived morphogenetic protein-1
- growth differentiation factor 5
- growth/differentiation factor 5
BMPs (bone morphogenetic proteins) belong to the TGF-Beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development. Recombinant human BMP-14 is a 27 kDa homodimeric protein consisting of two 120 amino acid polypeptide chains.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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