GATE-16/GABARAPL2 Antibody

Product Discontinued

GATE-16/GABARAPL2 Antibody Summary

• Immunogen: A synthetic peptide (CVESAKIRAKYP) corresponding to the N-terminal of human GABARAP L2 (GABARAPL2) protein has been used as the immunogen. The sequence is homologous with mouse and rat form of GABARAP L2 (GABARAPL2).
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GABARAPL2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:200-1:1000
  • Immunohistochemistry 1:200-1:1000
  • Western Blot 1:200-1:1000
• Theoretical MW: 14 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, rat. Predicted cross-reactivity based on antigen sequence identity: Mouse (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Please contact technical support for detailed reconstituion instruction.

Alternate Names for GATE-16/GABARAPL2 Antibody

• Apg8p2
• ATG8
• ATG8C
• FLC3A
• GABARAPL2
• gamma-aminobutyric acid receptor-associated protein-like 2
• Ganglioside expression factor 2
• GATE16
• GATE-16
• GEF2
• GEF-2
• GEF2GEF-2
• General Protein Transport Factor P16
• Golgi-Associated ATPase Enhancer Of 16 KDa
• MAP1 light chain 3 related protein
• MAP1 light chain 3-related protein

Background

FUNCTION: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. SUBUNIT: Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin. Interacts with ULK1. SUBCELLULAR LOCATION: Golgi apparatus. TISSUE SPECIFICITY: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. SIMILARITY: Belongs to the MAP1 LC3 family.



This product is distributed on behalf of Biosensis Pty. Ltd. of Australia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GATE-16/GABARAPL2 Antibody (R-142-100)(4)

Publications using R-142-100

• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (Human)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.
• The MGC Project Team. Genome Res. 14:2121-2127. 2004-01-01 [PMID: 15489334]
• Xin Y et al. Genomics 74:408-413. 2001-01-01 [PMID: 11414770]
• Okazaki N et al. Brain Res. Mol. Brain Res. 85:1-12. 2000-01-01 [PMID: 11146101]

FAQs for GATE-16/GABARAPL2 Antibody (R-142-100). (Showing 1 - 1 of 1 FAQs).

1. I am currently interested in detecting GABARAPL2 by immunofluorescence. Do you have an antibody that I could try out for immunofluorescence
   • Here is the link using our search bar and filters

Bioinformatics

• Gene Symbol: GABARAPL2
• Entrez:
  • 11345(Human)
  • 93739(Mouse)
  • 64670(Rat)
• Uniprot:
  • P60520()