Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody

Images

 
Immunohistochemistry-Paraffin: Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody [NLS830] - Human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry: Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody [NLS830] - Analysis of anti-GRPR antibody with human pancreas, islet of Langerhans at 4 ug/ml.
Immunohistochemistry-Paraffin: Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody [NLS830] - Analysis of anti-GRPR antibody with human lung, non-small cell carcinoma.

Product Details

Summary
Reactivity Hu, Po, Bt, Ca, Eq, Mk, Pm, Rb, BvSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from 2nd extracellular domain of human GRPR.
Specificity
Human GRPR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Bovine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000 - 1:10000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 4 ug/ml
Publications
Read Publications using NLS830.

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Mouse (83%), Rat (83%), Hamster (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody

  • BN
  • Bombesin
  • Gastrinreleasing Peptide
  • Gastrin-releasing Peptide
  • GRP
  • GRP10
  • GRP-10
  • neuromedin C
  • pre-progastrin releasing peptide
  • preproGRP
  • proGRP

Background

Gastrin-releasing peptide receptor (GRPR) is a Bombesin Receptor. In addition to its involvement in autism and mental retardation, GRPR may also play a role in the progression of cancer. Nicotine exposure induces an increase in GRPR expression in the lung Shriver et al. (2000). GRPR has been reported in brain, breast, colon, lung, lymph node, ovary, placenta, prostate, stomach, and uterus. It has also been shown to be expressed in several cancers, including those in breast, colon, lung, ovary, pancreas, and prostate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody (NLS830)(2)

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRP
Uniprot