GAP-43 [p Ser41] Antibody


Western Blot: GAP-43 [p Ser41] Antibody [NBP1-51473] - Analysis of p-GAP-43 (S41) pAb at 1:500 dilution Lane1:Hela cell lysate treated with PMA (100nM,30mins) Lane2:Raw264.7 cell lysate treated with PMA more
Immunohistochemistry-Paraffin: GAP-43 [p Ser41] Antibody [NBP1-51473] - Paraffin-embedded human breast carcinoma tissue at 1:50.showing cell membrane staining. Negative control (the right) Using PBS instead of primary more

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
1.0 mg/ml

Order Details

GAP-43 [p Ser41] Antibody Summary

Synthetic phosphopeptide derived from human GAP43 around the phosphorylation site of Serine 41.
p Ser41
Neuronal Marker
p-GAP-43 (S41) pAb detects endogenous levels of GAP-43 protein only when phosphorylated at S41.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Phosphate buffered saline (PBS) approx. pH 7.2.
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
38 kDa

Alternate Names for GAP-43 [p Ser41] Antibody

  • Axonal membrane protein GAP-43
  • B-50
  • Basp2
  • calmodulin-binding protein P-57
  • GAP43
  • growth associated protein 43
  • Growth-associated protein 43
  • nerve growth-related peptide GAP43
  • Neural phosphoprotein B-50
  • Neuromodulin
  • neuron growth-associated protein 43
  • PP46
  • protein F1


GAP-43 is a neural protein kinase C (PKC) substrate enriched in nerve growth cones that is implicated in growth cone plasticity. Endogenous growth cone GAP-43 is phosphorylated at multiple sites, on both Serine and Threonine residues. Stimulation of PKC activity increases the phosphorylation of only those proteolytic fragments containing Ser 41. However, phosphorylation is predominantly associated with fragments not containing Ser 41. Casein kinase II (CKII) phosphorylates GAP-43 at Serines 191/192 and Threonines 88, 89 and/or 95 both in vitro and in neuronal growth cones. Thus, GAP-43 in growth cones is not only a substrate for PKC, but also for CKII. Basic fibroblast growth factor promotes GAP-43 translocation from the cytosol to adherent membrane patches and stimulates GAP-43 phosphorylation, mainly at Ser 41. The stimulation of neurite outgrowth by NCAM also requires GAP-43 function; and GAP-43 phosphorylation in isolated grow.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Product PDFs


Gene Symbol GAP43

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