GALE Antibody (1C4)

Images

 
Western Blot: GALE Antibody (1C4) [NBP2-03390] Analysis of extracts (35ug) from 9 different cell lines by using anti-GALE monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: ...read more
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Human prostate tissue using anti-GALE mouse monoclonal antibody.
Western Blot: GALE Antibody (1C4) [NBP2-03390] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GALE (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ...read more
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GALE mouse monoclonal antibody.
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-GALE mouse monoclonal antibody.
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GALE mouse monoclonal antibody.
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-GALE mouse monoclonal antibody.
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Human Kidney tissue using anti-GALE mouse monoclonal antibody.
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Human liver tissue using anti-GALE mouse monoclonal antibody.
Immunohistochemistry-Paraffin: GALE Antibody (1C4) [NBP2-03390] - Staining of paraffin-embedded Human lymph node tissue using anti-GALE mouse monoclonal antibody.

Product Details

Summary
Reactivity Hu, Rt, Ca, PmSpecies Glossary
Applications WB, IHC, IHC-P
Clone
1C4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

GALE Antibody (1C4) Summary

Immunogen
Full length human recombinant protein of human GALE (NP_000394) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GALE
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human, Dog, Rat, Monkey

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GALE Antibody (1C4)

  • EC 5.1.3
  • EC 5.1.3.2
  • FLJ95174
  • FLJ97302
  • Galactowaldenase
  • short chain dehydrogenase/reductase family 1E, member 1
  • UDP galactose-4'-epimerase
  • UDP-
  • UDP-galactose 4-epimerase
  • UDP-galactose-4-epimerase
  • UDP-glucose 4-epimerase

Background

This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GALE
Entrez