GABA-A R alpha 5 Antibody

Images

 
Western Blot: GABA-A R alpha 5 Antibody [NBP2-16567] - Sample (30 ug of whole cell lysate) A: NT2D1 B: PC-3 C: U87-MG D: SK-N-SH 10% SDS PAGE gel, diluted at 1:3000.
Immunohistochemistry-Paraffin: GABA-A R alpha 5 Antibody [NBP2-16567] - Immunohistochemical analysis of paraffin-embedded RF48 xenograft, using antibody at 1:500 dilution.
Western Blot: GABA-A R alpha 5 Antibody [NBP2-16567] - Sample (30 ug of whole cell lysate) A: Neuro2A 10% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

GABA-A R alpha 5 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 5. The exact sequence is proprietary.
Localization
Cell junction; synapse; postsynaptic cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GABRA5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GABA-A R alpha 5 Antibody

  • GABA A R alpha 5
  • GABA(A) receptor subunit alpha-5
  • GABAAR alpha 5
  • GABAARa5
  • GABRA5
  • gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • gamma-aminobutyric acid receptor subunit alpha-5
  • MGC138184

Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GABRA5
Entrez
Uniprot