The purity of this protein is > 85% by SDS-PAGE. Molecular weight is 53.2kDa (474aa), confirmed by MALDI-TOF.
Alternate Names for G3BP1 Recombinant Protein
ATP-dependent DNA helicase VIII
G3BPRas-GTPase-activating protein SH3-domain-binding protein
GAP binding protein
GAP SH3 domain-binding protein 1
GTPase activating protein (SH3 domain) binding protein 1
ras GTPase-activating protein-binding protein 1
RasGAP-associated endoribonuclease G3BP
G3BP1 is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. And it cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. Recombinant human G3BP1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.