G3BP1 Antibody

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Western Blot: G3BP1 Antibody [NB100-75511] - E coli-derived fusion protein as test antigen. Affi-pure IgY dilution: 1:3000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-G3BP )

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-75511
    • Availability
      Product Discontinued

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G3BP1 Antibody Summary

Immunogen
The immunogen for this antibody was a sequence from 132a.a. to 350a.a. from G3BP(a 466a.a. long protein)
Localization
Cytoplasm (By similarity).
Specificity
G3BP
Clonality
Polyclonal
Host
Chicken
Gene
G3BP1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affi-pure IgY dilution: 1:3000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for G3BP1 Antibody

  • ATP-dependent DNA helicase VIII
  • EC 3.6.1
  • EC 3.6.4.12
  • EC 3.6.4.13
  • G3BP-1
  • G3BPRas-GTPase-activating protein SH3-domain-binding protein
  • GAP binding protein
  • GAP SH3 domain-binding protein 1
  • GTPase activating protein (SH3 domain) binding protein 1
  • hDH VIII
  • HDH-VIII
  • MGC111040
  • ras GTPase-activating protein-binding protein 1
  • RasGAP-associated endoribonuclease G3BP

Background

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves c-myc mRNA preferentially at the 3'UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5' and 3' ends. Unwinds DNA/DNA. RNA/DNA. and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol G3BP1
Entrez
Uniprot