G-CSF Recombinant Protein Summary
A recombinant protein to G-CSF.
Amino Acid Sequence: MTPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP
|Details of Functionality
The proliferative activity of rhG-CSF is tested in culture using mouse bone marrow cells.
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Liquid. In phosphate-buffered Saline(PBS), pH7.4,10% glycerol
The purity of this protein is > 95% by SDS-PAGE. Molecular weight is 18.8kDa (175aa), confirmed by MALDI-TOF.
Alternate Names for G-CSF Recombinant Protein
- chromosome 17 open reading frame 33
- colony stimulating factor 3 (granulocyte)
- granulocyte colony-stimulating factor
Human granulocyte colony-stimulating factor(hG-CSF) is one of the hematopoietic growth factors which plays an important role in stimulating proliferation, differentiation, and functional activation of blood cells. In addition to its effect on hematopoiesis, G-CSF also enhances neutrophil functions against bacteria, fungi, and tumor cells mediated by antibody-dependent cell-mediated cytotoxicity. Recombinant hG-CSF was expressed in E.coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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