FoxP3 Antibody (FXP3/197) [DyLight 405LS]


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Product Details

Reactivity Hu, Mu, PmSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

FoxP3 Antibody (FXP3/197) [DyLight 405LS] Summary

Full-length human FOXP3 protein
Nuclear and Cytoplasmic
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
IgG1 Kappa
Protein A purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 405LS
DyLight 405LS (A=397, E=572)
50mM Sodium Borate
0.05% Sodium Azide
Protein A purified


  • Western Blot
Theoretical MW
51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Alternate Names for FoxP3 Antibody (FXP3/197) [DyLight 405LS]

  • AIID
  • AIIDMGC141961
  • forkhead box P3
  • Forkhead Box Protein P3
  • FOXP3delta7
  • immune dysregulation, polyendocrinopathy, enteropathy, X-linked
  • Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked
  • IPEX
  • JM2
  • MGC141961
  • MGC141963
  • PIDX
  • PIDXMGC141963
  • scurfin
  • XPID
  • XPIDpolyendocrinopathy, enteropathy, X-linked


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for FoxP3 Antibody (NBP2-34620V3). (Showing 1 - 2 of 2 FAQ).

  1. Does FoxP3 antibodies comes in lyophilized form?
    • FoxP3 antibodies, aka JM2 IPEX, and Scurfin antibodies, have the following products in lyophilized form: NBP1-18319, AF3240.
  2. What the theoretical molecular weight for FoxP3 antibodies?
    • The TMW of FoxP3 antibodies is approximately 47 - 52 kDa.

Secondary Antibodies


Isotype Controls

Additional FoxP3 Products

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Bioinformatics Tool for FoxP3 Antibody (NBP2-34620V3)

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Diseases for FoxP3 Antibody (NBP2-34620V3)

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PTMs for FoxP3 Antibody (NBP2-34620V3)

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Research Areas for FoxP3 Antibody (NBP2-34620V3)

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Blogs on FoxP3.

Is has been established that the regulatory transcription factor FOXP3 (a member of the forkhead/winged-helix family of transcription factors) is imperative to immune system homeostasis through CD4+CD25+ regulatory T cell function.  Distinctively,...  Read full blog post.

FOXP3: Master Regulatory Transcriptional Factor
FOXP3, a forkhead family transcription factor specially expressed in regulatory T (Treg) cells, controls the expression of many key immune-regulatory genes. Treg cells are a population of T lymphocytes that have critical roles in the immune system hom...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol FOXP3

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