FMRP Antibody (5B9)

Images

 
Western Blot: FMRP Antibody (5B9) [NBP2-01836] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMRP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ...read more
Immunocytochemistry/ Immunofluorescence: FMRP Antibody (5B9) [NBP2-01836] Staining of COS7 cells transiently transfected by pCMV6-ENTRY FMRP.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Human tonsil using anti-FMRP mouse monoclonal antibody.
Flow Cytometry: FMRP Antibody (5B9) [NBP2-01836] - Analysis of Jurkat cells, using anti-FMRP antibody, (Red), compared to a nonspecific negative control antibody (Blue).
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMRP mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMRP mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMRP mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMRP mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMRP mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Human Kidney tissue using anti-FMRP mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Human pancreas tissue using anti-FMRP mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FMRP Antibody (5B9) [NBP2-01836] - Staining of paraffin-embedded Human prostate tissue using anti-FMRP mouse monoclonal antibody.
Flow Cytometry: FMRP Antibody (5B9) [NBP2-01836] - Analysis of Hela cells, using anti-FMRP antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-01836
    • Availability
      Product Discontinued

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FMRP Antibody (5B9) Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FMR1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for FMRP Antibody (5B9)

  • FMRPFRAXAPOF
  • fragile X mental retardation 1 protein
  • fragile X mental retardation 1
  • MGC87458
  • POF1
  • premature ovarian failure 1
  • Protein FMR-1

Background

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol FMR1
Entrez