Recombinant Mouse Flt-3 Ligand Protein

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Summary
Product Discontinued
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    • Catalog Number
      NBP1-99706
    • Availability
      Product Discontinued

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Recombinant Mouse Flt-3 Ligand Protein Summary

Description
A recombinant protein corresponding to 144 amino acids of Mouse Flt-3 Ligand
Preparation
Method
>98% SDS-PAGE
Details of Functionality
Biological Activity: Determined by the dose dependent proliferation of mouse AML5 cells
Results: 5-8 ng/ml
Protein/Peptide Type
Recombinant Protein
Gene
FLT3LG
Purity
>90% SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and with no additives.
Concentration
Lyoph
Purity
>90% SDS-PAGE
Reconstitution Instructions
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml.

Notes

After reconstituted, dilute further with other aqueous solutions.

Alternate Names for Recombinant Mouse Flt-3 Ligand Protein

  • FL
  • Flt3 ligand
  • Flt-3 Ligand
  • Flt3L
  • FLT3LG
  • fms-related tyrosine kinase 3 ligand
  • SL cytokine

Background

Flt3-Ligand belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant form is the transmembrane which is biologically active on the cell surface. The proteolytically cleaved transmembrane isoform generates a soluble form, which is also biologically active. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. Recombinant murine flt3-Ligand is a 16.4 kDa protein containing 144 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol FLT3LG
Entrez