Recombinant Mouse Flt-3 Ligand Protein Summary
A recombinant protein corresponding to 144 amino acids of Mouse Flt-3 Ligand
|Details of Functionality
Biological Activity: Determined by the dose dependent proliferation of mouse AML5 cells
Results: 5-8 ng/ml
| Protein/Peptide Type
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
Sterile filtered and with no additives.
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml.
After reconstituted, dilute further with other aqueous solutions.
Alternate Names for Recombinant Mouse Flt-3 Ligand Protein
- Flt3 ligand
- Flt-3 Ligand
- fms-related tyrosine kinase 3 ligand
- SL cytokine
Flt3-Ligand belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant form is the transmembrane which is biologically active on the cell surface. The proteolytically cleaved transmembrane isoform generates a soluble form, which is also biologically active. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. Recombinant murine flt3-Ligand is a 16.4 kDa protein containing 144 amino acid residues.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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