Recombinant Human Flt-3 Ligand/FLT3L Protein

Product Discontinued

Recombinant Human Flt-3 Ligand/FLT3L Protein Summary

• Description: A recombinant protein corresponding to 155 amino acids of Human Flt-3 Ligand
• Preparation Method: >98% SDS-PAGE
• Details of Functionality: Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human AML5 cells is <1.0 ng/ml, corresponding to a specific activity of > 1 x 10^6 units/mg.
  Results: <1.0 ng/ml
• Protein/Peptide Type: Recombinant Protein
• Gene: FLT3LG
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Theoretical MW: 17.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml.

Notes

The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for Recombinant Human Flt-3 Ligand/FLT3L Protein

• FL
• FLG3L
• Flt3 ligand
• Flt-3 Ligand
• Flt3L
• FLT3LG
• fms-related tyrosine kinase 3 ligand
• SL cytokine

Background

Human flt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells. Recombinant human flt3-ligand is a soluble 17.6 kDa polypeptide containing 155 amino acid residues, which comprises the extraCellular domain of the transmembrane flt3-ligand protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: FLT3LG