FLAP Antibody

Images

 
Western Blot: FLAP Antibody [NBP1-30984] - Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: FLAP Antibody [NBP1-30984] - Paraffin-embedded OVCA xenograft, using antibody at 1:100 dilution.
Western Blot: FLAP Antibody [NBP1-30984] - Analysis of FLAP on Raji, diluted at 1:1000 with 12% SDS PAGE gel.

Product Details

Summary
Product Discontinued
View other related FLAP Primary Antibodies

Order Details


    • Catalog Number
      NBP1-30984
    • Availability
      Product Discontinued

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FLAP Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FLAP. The exact sequence is proprietary.
Localization
Nucleus membrane, Endoplasmic reticulum membrane
Clonality
Polyclonal
Host
Rabbit
Gene
ALOX5AP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Dot Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Tested in human and mouse. Predicted cross-reactivity based on sequence identity: Rat (86%), Pig (86%), Rhesus Monkey (86%), and Bovine (86%). Not yet tested in any other species.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for FLAP Antibody

  • arachidonate 5-lipoxygenase-activating protein
  • FLAPMK-886-binding protein

Background

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional FLAP Products

Bioinformatics Tool for FLAP Antibody (NBP1-30984)

Discover related pathways, diseases and genes to FLAP Antibody (NBP1-30984). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for FLAP Antibody (NBP1-30984)

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Pathways for FLAP Antibody (NBP1-30984)

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PTMs for FLAP Antibody (NBP1-30984)

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol ALOX5AP