FKBP51/FKBP5 Antibody (3E9)

Images

 
Western Blot: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FKBP5/FKBP51 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of ...read more
Immunocytochemistry/ Immunofluorescence: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] Staining of COS7 cells transiently transfected by pCMV6-ENTRY FKBP5/FKBP51.
Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded prostate tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded Carcinoma of thyroid tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded colon tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded endometrium tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody (3E9) [NBP1-47755] - Staining of paraffin-embedded pancreas tissue using anti-FKBP5/FKBP51 mouse monoclonal antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clone
3E9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

FKBP51/FKBP5 Antibody (3E9) Summary

Immunogen
Protein expressed in 293T cell transfected with human FKBP5 expression vector
Specificity
This antibody is specific for Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FKBP5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for FKBP51/FKBP5 Antibody (3E9)

  • 51 kDa FKBP
  • 54 kDa progesterone receptor-associated immunophilin
  • AIG6,51 kDa FK506-binding protein
  • Androgen-regulated protein 6
  • Dit1
  • FF1 antigen
  • FK506 binding protein 5
  • FK506-binding protein 5
  • FKBP5
  • FKBP-5
  • FKBP51
  • FKBP-51
  • FKBP51PPIase FKBP5
  • FKBP54
  • FKBP54EC 5.2.1.8
  • HSP90-binding immunophilin
  • MGC111006
  • p54
  • P54,51 kDa FK506-binding protein 5
  • peptidyl-prolyl cis-trans isomerase FKBP5
  • peptidylprolyl cis-trans isomerase
  • PPIase
  • Ptg-10
  • rotamase
  • T-cell FK506-binding protein

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ICC/IF Video Protocol

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Bioinformatics

Gene Symbol FKBP5
Entrez