Ficolin-1 Antibody

Images

 
Western Blot: Ficolin-1 Antibody [NBP1-45567] - Analysis of Ficolin-1 in 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 4).

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Ficolin-1 Antibody Summary

Immunogen
Synthetic peptide surrounding amino acid 320 of rat Ficolin-1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FCN1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~33 kDa Ficolin-1 and a 37 kDa Ficolin-1 precursor in samples from human, mouse and rat origins. Reactivity to other species has not been tested.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.5% BSA and 30% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Ficolin-1 Antibody

  • Collagen/fibrinogen domain-containing protein 1
  • FCN1
  • Fcna
  • FCNM
  • FCNMficolin-A
  • ficolin (collagen/fibrinogen domain containing) 1
  • ficolin (collagen/fibrinogen domain-containing) 1
  • Ficolin1
  • Ficolin-1
  • Ficolin-A
  • ficolin-alpha
  • M-ficolin

Background

M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol FCN1
Entrez
Uniprot