Fibronectin Antibody (5G7) [Alkaline Phosphatase]

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Product Details

Summary
Product Discontinued
View other related Fibronectin Primary Antibodies

Order Details


    • Catalog Number
      NBP1-26572
    • Availability
      Product Discontinued

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Fibronectin Antibody (5G7) [Alkaline Phosphatase] Summary

Immunogen
The immunogen is a peptide made to the amino acid region Fibronectin
Marker
Mesenchymal Cells Marker
Specificity
Reacts with Human Fibronectin. Cross reactivity with other species has not been established.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FN1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:500-1:1000

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50 mM Tris (pH 8.0), 1 mM MgCl2, and 50% Glycerol
Preservative
0.1% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Fibronectin Antibody (5G7) [Alkaline Phosphatase]

  • Fibronectin
  • FN1

Background

Fibronectin is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. They occur as dimers of two 250 kDa subunits. They have binding domains for bacterial proteins, collagens, heparin-like molecules and fibrin. Cellular fibronectin is widely distributed in the stroma of malignant tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Fibronectin/Anastellin Antibody (NBP1-26572) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Fibronectin/Anastellin Antibody (NBP1-26572)

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Diseases for Fibronectin/Anastellin Antibody (NBP1-26572)

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Blogs on Fibronectin.

Alpha-smooth muscle actin and the modulation of endothelial and epithelial cell biology
Actin is essential for a wide range of cell functions, ranging from cell division and chromatin remodeling to vesicle trafficking and maintenance of cellular structure. In fact, mislocalization of actin to cell junctions during development leads t...  Read full blog post.

Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...  Read full blog post.

Fibronectin: Organizing Cell Activity across the ECM
Fibronectin is a glycoprotein found in the extracellular matrix (ECM) that binds to integrins and other components of the ECM such as collagen and fibrin. Under normal physiological conditions, fibronectin is an important factor in cell adhesion, grow...  Read full blog post.

Using the Laminin Antibody in Angiogenesis Research
Laminin is one of a large number of proteins expressed on the basal laminar of the ECM (extracellular matrix). The laminin antibody database covers several proteins, which interact with integrins and other receptor proteins to support cellular differe...  Read full blog post.

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Bioinformatics

Gene Symbol FN1
Entrez