FGF R4 Antibody


Western Blot: FGFR4 Antibody [NBP2-16483] - Sample (30 ug of whole cell lysate) A: Molt-4 7. 5% SDS PAGE gel, diluted at 1:1000.

Product Details

Reactivity HuSpecies Glossary
Applications WB
0.95 mg/ml

Order Details

FGF R4 Antibody Summary

Recombinant fragment corresponding to a region within amino acids 315 and 556 of FGFR-4 (Uniprot ID#P22455)
Membrane; Single-pass type I membrane protein
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7).
0.01% Thimerosal
0.95 mg/ml
Immunogen affinity purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
88 kDa

Reactivity Notes

Human. Expected to cross react based on sequence identity: Mouse (86%), Rat (87%)

Alternate Names for FGF R4 Antibody

  • CD334 antigen
  • CD334
  • EC 2.7.10
  • EC
  • FGFR4
  • FGFR-4
  • fibroblast growth factor receptor 4
  • JTK2hydroxyaryl-protein kinase
  • MGC20292
  • protein-tyrosine kinase
  • TKF
  • tyrosine kinase related to fibroblast growth factor receptor
  • tyrosylprotein kinase


The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. [provided by RefSeq]


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol FGFR4

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