FGF R2 Antibody Summary
Recombinant protein encompassing a sequence within the C-terminus region of human FGFR2. The exact sequence is proprietary.
Cell membrane; Single-pass type I membrane protein; Isoform 14: Secreted; Isoform 19: Secreted
Mouse (99%), Rat (98%), Porcine (97%), Bovine (98%), Chicken (97%), Canine (99%), Xenopus (90%). Backed by our 100% Guarantee.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1:500-1:3000
- Immunohistochemistry 1:100-1:1000
- Immunohistochemistry-Paraffin 1:100-1:1000
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Xenopus laevis (90%), Zebrafish (89%), Rabbit (84%).
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Immunogen affinity purified
Alternate Names for FGF R2 Antibody
- CD332 antigen
- craniofacial dysostosis 1
- EC 2.7.10
- EC 22.214.171.124
- FGF R2
- fibroblast growth factor receptor 2
- Jackson-Weiss syndrome
- Keratinocyte growth factor receptorreceptor like 14
- soluble FGFR4 variant 4
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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