Recombinant Human FGF acidic/FGF1 Protein Summary
An un-tagged recombinant protein corresponding to the amino acids 16-155 of Human FGF acidic/FGF1
Amino Acid Sequence: MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
< 1.0 EU per 1 ug of protein (determined by LAL method)
|Details of Functionality
The ED50 for this effect is < 2.9 ng/ml, measured in a cell proliferation assay using NIH-3T3 cell (which corresponds to > 340,000 units/ml).
| Protein/Peptide Type
Biologically Active Protein
>95% pure by SDS-PAGE
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20 mM Tris, pH 7.0, 100 mM NaCl
>95% pure by SDS-PAGE
Alternate Names for Recombinant Human FGF acidic/FGF1 Protein
- ECGF-betaAcidic fibroblast growth factor
- endothelial cell growth factor, beta
- FGF acidic
- FGFABeta-endothelial cell growth factor
- fibroblast growth factor 1 (acidic)
- heparin-binding growth factor 1
Acidic fibroblast growth factor(aFGF) belongs to the fibroblast growth factor family. It is a potent mitogenic agent. aFGF has been detected in large amounts in the brain. Other cells known to express FGF acidic include hepatocytes, vascular smooth muscle cells, CNS neurons, skeletal muscle cells, fibroblasts, keratinocytes, endothelial cells, intestinal columnar epithelium cells and pituitary basophils and acidophils. The growth factor acts through activation of specific cell-surface receptors leading to intracellular tyrosine phosphorylation cascade. Recombinant human aFGF was overexpressed in E. coli and purified by conventional chromatography.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 2 years from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu, Rt
Applications: WB, Flow, IP, CyTOF-ready
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Applications: WB, Flow, CyTOF-ready
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Applications: WB, IHC
Publications for FGF acidic/FGF1 Biologically Active Protein (NBC1-18465) (0)
There are no publications for FGF acidic/FGF1 Biologically Active Protein (NBC1-18465).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for FGF acidic/FGF1 Biologically Active Protein (NBC1-18465) (0)
There are no reviews for FGF acidic/FGF1 Biologically Active Protein (NBC1-18465).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
- 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen
FAQs for FGF acidic/FGF1 Biologically Active Protein (NBC1-18465) (0)
Additional FGF acidic/FGF1 Products
Bioinformatics Tool for FGF acidic/FGF1 Biologically Active Protein (NBC1-18465)
Discover related pathways, diseases and genes to FGF acidic/FGF1 Biologically Active Protein (NBC1-18465). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on FGF acidic/FGF1