Fc gamma RIII (CD16) Antibody (MEM-154) [PE]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-81689
    • Availability
      Product Discontinued

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Fc gamma RIII (CD16) Antibody (MEM-154) [PE] Summary

Immunogen
Human granulocytes
Specificity
The antibody MEM-154 reacts with an epitope on CD16 antigen that is residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgammaRIII antigen). The antibody MEM-154 reacts with CD16+ granulocytes. HLDA V; WS Code M MA068 HLDA V; WS Code NK NK51
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FCGR3A
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 20 ul/10^6 cells
Positive Control
Fc gamma RIIIB/CD16b Lysate (NBL1-10659)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Purity
Protein A purified

Alternate Names for Fc gamma RIII (CD16) Antibody (MEM-154) [PE]

  • Fc gamma RIII
  • FcgRIII

Background

CD16 (FcgRIII) is a 26 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Diseases for Fc gamma RIIIA/CD16a Antibody (NB110-81689)

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Bioinformatics

Gene Symbol FCGR3A
Entrez