FANCG Antibody

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Immunohistochemistry-Paraffin: FANCG Antibody [NBP1-03283] - Staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-03283
    • Availability
      Product Discontinued

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FANCG Antibody Summary

Immunogen
Synthetic peptide from human FANCG.
Specificity
Amino acids 1-12 of human FANCG protein.
Clonality
Polyclonal
Host
Rabbit
Gene
FANCG
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:10000-1:50000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5-25 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.2) and 0.15M NaCl
Preservative
0.01% Sodium Azide
Concentration
0.93 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FANCG Antibody

  • DNA repair protein XRCC9
  • FAG
  • Fanconi anemia group G protein
  • Fanconi anemia, complementation group G
  • Protein FACG
  • X-ray repair, complementing defective, in Chinese hamster, 9
  • XRCC9X-ray repair complementing defective repair in Chinese hamster cells 9

Background

FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies caused by defects in the FANCG gene. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FANCG Antibody (NBP1-03283) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional FANCG Products

Bioinformatics Tool for FANCG Antibody (NBP1-03283)

Discover related pathways, diseases and genes to FANCG Antibody (NBP1-03283). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for FANCG Antibody (NBP1-03283)

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Pathways for FANCG Antibody (NBP1-03283)

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PTMs for FANCG Antibody (NBP1-03283)

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Research Areas for FANCG Antibody (NBP1-03283)

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Blogs on FANCG.

Fanconi Antibodies and Cancer Research
We at Novus Biologicals have an extensive antibody databasedevoted to the 13 Fanconi anaemia complementation (FANC) genes, which are involved in the recognition and repair of damaged DNA.The core complex of 8 proteins (FANCA, B, C, E, F, G, L and M)...  Read full blog post.

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Bioinformatics

Gene Symbol FANCG
Entrez
Uniprot