Western Blot: FAK Antibody [NBP1-72238] - The cell lysate derived from pervanadate treated 3T3 was resolved onto 7.5% SDSPAGE, transferred onto NC membrane, and followed by an immunoblotting with Rabbit anti FAK (pY576) ...read more
125 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NBP1-72238 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Sterile TBS (pH 7.2) with antibody stabilizer
Immunogen affinity purified
Alternate Names for FAK [p Tyr576] Antibody
FADKFAK-related non-kinase polypeptide
focal adhesion kinase 1
Protein-tyrosine kinase 2
PTK2 protein tyrosine kinase 2
Focal adhesion kinase (FAK) gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinase but lacks significant sequence similarity to kinase from other subfamilies. Activation by phosphorylation of Y397, Y576/577 and Y863 of FAK protein may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Increased FAK expression has been correlated with the enhanced motility and invasiveness of human tumor cells, as well as with promoting increased cell proliferation
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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