FAK Antibody

Images

 
Immunohistochemistry-Paraffin: FAK Antibody [NB110-39018] - Anti-FAK / Focal Adhesion Kinase antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more
Immunohistochemistry-Paraffin: FAK Antibody [NB110-39018] - Analysis of anti-FAK / Focal Adhesion Kinase antibody with human lobular epithelium at concentration 6 ug/ml.
Immunohistochemistry-Paraffin: FAK Antibody [NB110-39018] - Analysis of anti-FAK / Focal Adhesion Kinase antibody with human brain, glioblastoma.

Product Details

Summary
Reactivity Hu, Mu, Pm, Rt, Bt, Bv, Ca, Eq, Op, RbSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

FAK Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from C-terminus of human FAK.
Epitope
C-terminal region of human.
Marker
Focal Adhesion Marker
Specificity
Human FAK. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Rat (94%), Canine (94%), Bat (94%), Equine (94%), Opossum (94%), Bovine (94%), Rabbit (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTK2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 6 ug/ml

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (94%), Platypus (94%), Hamster (88%), Xenopus (88%), Turkey (81%), Chicken (81%), Pufferfish (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FAK Antibody

  • EC 2.7.10
  • FADK 1
  • FADK1
  • FADKFAK-related non-kinase polypeptide
  • FAK
  • FAK1FRNK
  • FAKEC 2.7.10.2
  • focal adhesion kinase 1
  • pp125FAK
  • Protein-tyrosine kinase 2
  • PTK2 protein tyrosine kinase 2
  • PTK2

Background

Focal adhesion kinase (FAK) is a non-receptor protein-tyrosine kinase that is involved in signaling pathways involved in cell motility, proliferation, and apoptosis. FAK is activated by tyrosine phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. FAK plays a potential role in oncogenic transformation resulting in increased kinase activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: IHC-P

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PTK2
Entrez