ErbB4/Her4 Antibody

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Immunohistochemistry-Paraffin: ErbB4/Her4 Antibody [NB110-39010] - Analysis of anti-ERBB4 antibody with human glomerulus at concentration 30 ug/ml.

Product Details

Summary
Reactivity Hu, Bt, Eq, Mk, Op, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

ErbB4/Her4 Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from internal region of human ERBB4.
Epitope
Human
Localization
Internal domain of human.
Specificity
Human ERBB4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Monkey (95%), Equine (95%), Opossum (100%), Primate (100%), Bat (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERBB4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 30 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Panda (100%), Mouse (89%), Rat (89%), Hamster (89%), Porcine (89%), Chicken (89%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ErbB4/Her4 Antibody

  • avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4
  • EC 2.7.10
  • EC 2.7.10.1
  • ErbB4
  • HER4
  • HER4MGC138404
  • p180erbB4
  • Proto-oncogene-like protein c-ErbB-4
  • receptor tyrosine-protein kinase erbB-4
  • Tyrosine kinase-type cell surface receptor HER4
  • v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Background

ERBB-4 receptor tyrosine kinase is activated by neuregulins, nrg- 2, nrg-3, heparin-binding egf-like growth factor, betacellulin and ntak to regulate cell proliferation and differentiation. Several isoforms of the ERBB-4 receptor tyrosine kinase have been identified and differ functionally in their response to phorbol ester: they represent cleavable and noncleavable forms of the receptor. These isoforms are differentially expressed in tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ERBB4
Entrez