ERAB Antibody (OTI5E2)


Western Blot: ERAB Antibody (5E2) [NBP2-02230] Analysis of extracts (35ug) from 9 different cell lines by using anti-ERAB monoclonal antibody.
Immunocytochemistry/ Immunofluorescence: ERAB Antibody (5E2) [NBP2-02230] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY ERAB.
Immunohistochemistry-Paraffin: ERAB Antibody (5E2) [NBP2-02230] - Staining of paraffin-embedded liver tissue using anti-ERAB mouse monoclonal antibody.
Flow Cytometry: ERAB Antibody (5E2) [NBP2-02230] - Analysis of Hela cells, using anti-ERAB antibody, (Red) compared to a nonspecific negative control antibody (Blue).
Western Blot: ERAB Antibody (5E2) [NBP2-02230] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ERAB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 more
Immunohistochemistry-Paraffin: ERAB Antibody (5E2) [NBP2-02230] - Staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-ERAB mouse monoclonal antibody.
Immunohistochemistry-Paraffin: ERAB Antibody (5E2) [NBP2-02230] - Staining of paraffin-embedded Carcinoma of liver tissue using anti-ERAB mouse monoclonal antibody.

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ERAB Antibody (OTI5E2) Summary

Full length human recombinant protein of human HSD17B10 (NP_004484) produced in HEK293T cell.
Immunogen affinity purified
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  • Western Blot 1:2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

Human, Monkey

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
0.02% Sodium Azide
Immunogen affinity purified

Alternate Names for ERAB Antibody (OTI5E2)

  • 17-beta-HSD 10
  • 17-beta-hydroxysteroid dehydrogenase 10
  • 17b-HSD10
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • ABAD
  • amyloid-beta peptide binding alcohol dehydrogenase
  • CAMR
  • DUPXp11.22
  • EC
  • EC
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • ERAB3-hydroxyacyl-CoA dehydrogenase type-2
  • HADH2AB-binding alcohol dehydrogenase
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II
  • hydroxysteroid (17-beta) dehydrogenase 10
  • mental retardation, X-linked, syndromic 10
  • MHBD
  • Mitochondrial ribonuclease P protein 2,3-hydroxyacyl-CoA dehydrogenase type II
  • Mitochondrial RNase P protein 2
  • MRX17
  • MRX31
  • MRXS10
  • SDR5C1
  • short chain dehydrogenase/reductase family 5C, member 1
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
  • short chain type dehydrogenase/reductase XH98G2
  • Short-chain type dehydrogenase/reductase XH98G2
  • Type II HADH
  • XH98G2


This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol HSD17B10