ER alpha/NR3A1 Antibody (5D4B1)

Images

 
Western Blot: ER alpha/NR3A1 Antibody (5D4B1) [NBP1-47372] - Analysis using ER mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ER cDNA (2).
Western Blot: ER alpha/NR3A1 Antibody (5D4B1) [NBP1-47372] - Analysis using ER mouse mAb truncated ER recombinant protein (1) MCF-7 cell lysates (2).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-47372
    • Availability
      Product Discontinued

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ER alpha/NR3A1 Antibody (5D4B1) Summary

Immunogen
Purified recombinant fragment of ER expressed in E. Coli.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ESR1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1: 500 - 1:2000
  • ELISA 1:10000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for ER alpha/NR3A1 Antibody (5D4B1)

  • ER alpha
  • ER
  • Era
  • ER-alpha
  • ESR1
  • ESRESRA
  • Estradiol receptor
  • estrogen receptor 1
  • estrogen receptor alpha delta 3*4,56,7*/819-2 isoform
  • estrogen receptor alpha delta 4 +49 isoform
  • estrogen receptor alpha delta 4*5,6,7*/654 isoform
  • estrogen receptor alpha
  • estrogen receptor
  • NR3A1
  • NR3A1DKFZp686N23123
  • Nuclear receptor subfamily 3 group A member 1

Background

The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics Tool for Estrogen Receptor Antibody (NBP1-47372)

Discover related pathways, diseases and genes to Estrogen Receptor Antibody (NBP1-47372). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Estrogen Receptor Antibody (NBP1-47372)

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Bioinformatics

Gene Symbol ESR1
Entrez