EphB6 Antibody (9B17)

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Immunohistochemistry-Paraffin: EphB6 Antibody (9B17) [NB110-93608] - Paraffin lung and kidney sections from LPS treated mice.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC-P
Clone
9B17
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

EphB6 Antibody (9B17) Summary

Immunogen
Recombinant mouse EPH Receptor B6 Antibody (9B17) extracellular domain
Specificity
This was selected for its ability to detect mouse EPH Receptor B6 Antibody (9B17) in western blots. In this format, this does not cross-react with recombinant mouse EphA2, EphA3, EphA4, EphA6, EphA7 EphA8, EphB2, EphB3 or EphB4.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
EPHB6
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Reacts with Mouse.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for EphB6 Antibody (9B17)

  • EC 2.7.10.1
  • EPH receptor B6
  • EphB6
  • ephrin type-B receptor 6
  • Hep
  • HEPTyrosine-protein kinase-defective receptor EPH-6
  • Mep
  • MGC129910
  • MGC129911

Background

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol EPHB6
Entrez