EphA7 Antibody

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Western Blot: EPH Receptor A7 Antibody [NB100-92384] - Western blot (WB) analysis of EPH Receptor A7 (E477) antibody in extracts from Jurkat cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-92384
    • Availability
      Product Discontinued

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EphA7 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 443-495 of Human EphA7.
Clonality
Polyclonal
Host
Rabbit
Gene
EPHA7
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of EPH Receptor A7 (E477) pAb in extracts from Jurkat cells.
Theoretical MW
112 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for EphA7 Antibody

  • Cek11
  • Ebk
  • EC 2.7.10
  • EC 2.7.10.1
  • Ehk3
  • EHK-3
  • EK11
  • EPH homology kinase 3
  • Eph homology kinase-3
  • EPH receptor A7
  • EphA7
  • EPH-like kinase 11
  • ephrin type-A receptor 7
  • Hek11
  • Mdk1
  • receptor protein-tyrosine kinase HEK11
  • tyrosine-protein kinase receptor EHK-3

Background

The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8(Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5(Hek9) and EphB6 (Mep). EphAs are a family of receptor tyrosine kinases that are involved in axonal guidance during development. These receptors and their ligands, the ephrins, act via repulsive mechanisms to guide growing axons towards their appropriate targets and allow for the correct developmental connections to be made. Ligand binding to an Eph receptor results in tyrosine phosphorylation of the kinase domain, and repulsion of axonal growth cones and migrating cells. During neurulation, ephrin-A5 is coexpressed with its cognate receptor EphA7 in cells at the edges of the dorsal neural folds. Three different EphA7 splice variants, a full-length form and two truncated versions lacking kinase domains, are expressed in the neural folds.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EPHA7
Entrez