EphA2 Antibody (SP169)

Images

 
Immunohistochemistry-Paraffin: EPH Receptor A2 Antibody (SP169) [NBP2-21760] - Human breast carcinoma.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clone
SP169
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

EphA2 Antibody (SP169) Summary

Immunogen
Synthetic peptide derived from the internal region of human EphA2 protein.
Localization
Membrane
Clonality
Monoclonal
Host
Rabbit
Gene
EPHA2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
Theoretical MW
135 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Tested in Human. Based on sequence identity cross reactivity is expected with Primate and Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.6) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Protein A or G purified

Alternate Names for EphA2 Antibody (SP169)

  • ARCC2
  • EC 2.7.10
  • EC 2.7.10.1
  • Eck
  • ECKepithelial cell receptor protein tyrosine kinase
  • EPH receptor A2
  • EphA2
  • ephrin type-A receptor 2
  • Epithelial cell kinase
  • Myk2
  • Sek2
  • soluble EPHA2 variant 1
  • Tyrosine-protein kinase receptor ECK

Background

Ephrin type-A receptor 2 (EphA2) is a protein-tyrosine kinase in the ephrin receptor subfamily. EphA2 plays a role for angiogenesis and tumor neovascularization. High levels of EphA2 protein expression can be detected in some tumor cells such as breast carcinoma, bladder carcinoma, renal cell carcinoma (RCC), and non-small cell lung carcinoma (NSCLC). Inhibition of EphA2 kinase activity is considered for the treatment of various tumors such as RCC and NSCLC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EPHA2
Entrez