Endostatin Antibody (91318)

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Product Details

Summary
Reactivity Hu, Mu, ChSpecies Glossary
Applications WB, ELISA
Clone
91318
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Endostatin Antibody (91318) Summary

Immunogen
Purified recombinant mouse endostatin, expressed in insect Sf 21 cells.
Localization
Cytoplasmic and Nuclear
Specificity
Rat Monoclonal to Endostatin (91318)
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
COL18A1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Application Notes
ELISA: Use at a concentration of 0.5 - 1 ug/ml. The detection limit for recombinant mouse endostatin is approximately 6 ng/well. WB: Use at a concentration of 1 - 2 ug/ml. The detection limit for recombinant mouse endostatin is approximately 50 ng/lane and 5 ng/lane under non-reducing and reducing conditions, respectively. Predicted molecular weight: 22 kDa.
Publications
Read Publication using
NB120-10604 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 5% Trehalose
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for Endostatin Antibody (91318)

  • antiangiogenic agent
  • COL18A1
  • collagen alpha-1(XVIII) chain
  • collagen, type XVIII, alpha 1
  • Endostatin
  • FLJ27325
  • FLJ34914
  • human type XVIII collagen10endostatin
  • KNO
  • KNO1MGC74745
  • Knobloch syndrome, type 1
  • KS
  • multi-functional protein MFP

Background

Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Endostatin Antibody (NB120-10604)(1)

We have publications tested in 2 confirmed species: Human, Chicken.

We have publications tested in 1 application: WB.


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WB
(1)
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(1)
Chicken
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol COL18A1
Entrez