EGF R/ErbB1 Antibody


Immunohistochemistry-Paraffin: EGF R/ErbB1 Antibody [NBP1-50332] - Analysis of anti-EGFR antibody with human placenta at concentration 5 ug/ml.

Product Details

Reactivity HuSpecies Glossary
Applications WB, IHC-P, IP, ICC
1 mg/ml

Order Details

EGF R/ErbB1 Antibody Summary

A 20 amino acid synthetic peptide of human EGFr representing a portion of the internal domain proximal to a phosphorylation region.
This EGFr antibody recognizes a region of the internal domain. Antibody binding blocks phosphorylation and does not interfere with EGF binding.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
1 mg/ml
Protein G purified


  • Western Blot 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Immunoprecipitation 10 - 12 ug/ml
  • Immunocytochemistry 1:10 - 1:500

Alternate Names for EGF R/ErbB1 Antibody

  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
  • cell growth inhibiting protein 40
  • cell proliferation-inducing protein 61
  • EC 2.7.10
  • EC
  • EGFR
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog)
  • epidermal growth factor receptor
  • ERBB
  • ErbB1
  • ERBB1PIG61
  • HER1
  • HER-1
  • mENA
  • Proto-oncogene c-ErbB-1
  • Receptor tyrosine-protein kinase erbB-1


The EGFR is a ubiquitously expressed 180 kD membrane tyrosine kinase that dimerizes upon binding EGF, transforming growth factor alpha, or other ligands. Dimerization initiates downstream signaling that elicits extensive phosphorylation of the receptor resulting in mitogenesis and protection against apoptotic stimuli. EGF receptor expression is amplified in many squamous carcinomas and in the bronchi of high-risk smokers. The receptor is internalized and degraded after ligand binding. EGFR extensively interacts with a number of proteins and is also reported to be a cellular receptor for cytomegalovirus. The Poly6213 antibody recognizes the human, mouse, and rat EGFR and has been shown to be useful for Western blotting. Interacts with Grb2, SHP1 and 2, VAV2 and 3, FAK, c-Src, GAB1, NCK1, Shc, human cytomegalovirus and numerous other proteins.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies


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Gene Symbol EGFR

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