EGF R/ErbB1 Antibody (B1D8) [PE]

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Product Details

Summary
Reactivity Hu, Mu(-), Rt(-)Species Glossary
Applications Flow
Clone
B1D8
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

EGF R/ErbB1 Antibody (B1D8) [PE] Summary

Immunogen
Microsomes from A431 cells
Localization
Cell surface
Specificity
This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF??induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
EGFR
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Blocks Ligand-induced Activation of EGFR; Inhibits Proliferation of A431 Cells; Arrests Tumor Growth in vivo

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for EGF R/ErbB1 Antibody (B1D8) [PE]

  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
  • cell growth inhibiting protein 40
  • cell proliferation-inducing protein 61
  • EC 2.7.10
  • EC 2.7.10.1
  • EGF R
  • EGFR
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog)
  • epidermal growth factor receptor
  • ErbB
  • ErbB1
  • ERBB1PIG61
  • HER1
  • HER-1
  • mENA
  • Proto-oncogene c-ErbB-1
  • Receptor tyrosine-protein kinase erbB-1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EGFR
Entrez
Uniprot

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