EDC4 Antibody

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Immunoprecipitation: EDC4 Antibody [NB100-2274] - Detection of Human RCD8 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity ...read more

Product Details

Summary
Product Discontinued
View other related EDC4 Primary Antibodies

Order Details


    • Catalog Number
      NB100-2274
    • Availability
      Product Discontinued

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EDC4 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1351 and 1401 of human RCD8 Autoantigen using the numbering given in entry AAH43616 (GeneID 23644).
Clonality
Polyclonal
Host
Rabbit
Gene
EDC4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2-5 ug/mg lysate
Application Notes
This antibody is useful for Immunoprecipitation. Not recommended for Western Blot. Use Rabbit anti-RCD8 antibody NB 100-2273.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for EDC4 Antibody

  • Autoantigen Ge-1
  • Autoantigen RCD-8
  • enhancer of mRNA decapping 4
  • enhancer of mRNA-decapping protein 4
  • Ge-1
  • Hedls
  • HEDLSHuman enhancer of decapping large subunit
  • RCD-8

Background

EDC4 belongs to the WD repeat EDC4 family, it contains four WD repeats. In the process of mRNA degradation EDC4 seems to play a role in mRNA decapping. EDC4 is a component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. It promotes complex formation between DCP1A and DCP2, and enhances the catalytic activity of DCP2 (in vitro). There are two named isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EDC4
Entrez
Uniprot