EAAT1/GLAST-1/SLC1A3 Antibody


Western Blot: EAAT1/GLAST-1/SLC1A3 Antibody [NBP2-11258] - A) and hippocampal membranes (B). Apparent MW of Slc1A is 71kDa. Antibody dilution 1:500 in Diluition Buffer.

Product Details

Product Discontinued
View other related EAAT1/GLAST-1/SLC1A3 Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

EAAT1/GLAST-1/SLC1A3 Antibody Summary

Synthetic peptide taken from human Slc1A protein taken from within the C-terminal domain of Slc1A. The peptide was conserved in several other species. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker for immunogen preparation.
aa: ckvtlaangksadcsveeepwkrek
The antibody labels a strong diffuse band of Slc1A 71kDa in samples and in hippocampal membranes. The antibody also labels a weak band of 42kDa. The identity of this band is not known.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1:500
  • ELISA 1:500
Application Notes
Slc1A antibody was tested in ELISA and western blotting applications
Positive Control
EAAT1/GLAST-1/SLC1A3 Lysate (NBP2-64783)

Reactivity Notes

Human, Mouse and Rat

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Tris/Glycine buffer pH 7.5-7.9, stabilizing protein, and glycerol
0.02% Sodium Azide
0.5 mg/ml
Immunogen affinity purified

Alternate Names for EAAT1/GLAST-1/SLC1A3 Antibody

  • EA6
  • EA6FLJ25094
  • EAAT1
  • excitatory amino acid transporter 1
  • GLAST1
  • GLAST-1
  • SLC1A3
  • Sodium-dependent glutamate/aspartate transporter 1
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3
  • Solute carrier family 1 member 3


The Solute Carriers (SLCs) are membrane transport proteins that regulate transport of substances across the cell membrane such as sugars, amino acids, nucleotides, inorganic ions, and drugs. The Slc family members include genes that encode passive transporters, ion transporters, and exchangers. Slc transporter entirly rely on an ion gradient over the cell membrane as the driving force for transport across the membrane. The Slc's do not involve in primary active transport of solutes across the membrane (1). Excitatory amino acid transporters (EAATs) are high-affinity, sodium-dependent glutamate transport carriers from solute carrier family 1 (Slc1), primarily expressed in astroglia and are responsible for most of the glutamate transport in the adult brain (2). Glutamate transporters (the human homolog of which is excitatory amino acid transporter) are required in the termination of the synaptic actions of the neurotransmitter and keep its synaptic concentrations below neurotoxic levels. Glutamate transport is an electrogenic process consisting of two sequential translocation steps, co-transport of the neurotransmitter with three sodium ions and a proton and the counter-transport of one potassium ion. Glutamate transporters mediate substrate-induced steady-state current by the electrogenic transport. Non-transportable substrate analogs, expected to "lock" the transporter in an outward-facing conformation and are the competitive inhibitors of two types of substrate-induced current, and also inhibit the basal sodium-dependent anion conductance (3). The function of glutamate transporters is to regulate synaptic glutamate levels and to prevent excitotoxic neuronal death as a result of prolonged excitation of glutamate receptors. Slc1is a multi-trans-membrane-spanning protein that exist as multi subunit protein in membrane (4). Glutamate transporters are essential in preventing hyperexcitability and CNS neurotoxicity. Glutamate transporters (Slc1A) are responsible for clearing synaptically released glutamate at excitatory synapses. Slc1A reduce spillover, thus ensuring a spatially restricted action of glutamate and preventing its accumulation in the extracellular space. By these actions, Slc1A contribute to sculpting excitatory postsynaptic currents and to modulating synaptic plasticity. Slc1A isoform, exhibits the highest level of expression and is responsible for the largest proportion of glutamate transport in hippocampus. Slc1A down-regulation increases extracellular glutamate levels which in turn cause excitotoxicity, conversely, an elevated expression of Slc1A may be neuroprotective (5).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, In vivo
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Fe, GP, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu
Applications: IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Rt, Ca, Eq
Species: Hu
Applications: CyTOF-reported, ICC, ICFlow
Species: Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr
Species: Hu
Applications: WB, Simple Western, IHC
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Ca
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu
Applications: WB, CyTOF-ready, ICFlow
Species: Hu, Mu, Rt
Applications: WB, ELISA

Publications for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258) (0)

There are no publications for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258) (0)

There are no reviews for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Additional EAAT1/GLAST-1/SLC1A3 Products

Bioinformatics Tool for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258)

Discover related pathways, diseases and genes to EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258)

Discover more about diseases related to EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258).

Pathways for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258)

View related products by pathway.

PTMs for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258)

Learn more about PTMs related to EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258).

Research Areas for EAAT1/GLAST-1/SLC1A3 Antibody (NBP2-11258)

Find related products by research area.

Blogs on EAAT1/GLAST-1/SLC1A3

There are no specific blogs for EAAT1/GLAST-1/SLC1A3, but you can read our latest blog posts.

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our EAAT1/GLAST-1/SLC1A3 Antibody and receive a gift card or discount.


Gene Symbol SLC1A3