Dystrophin Antibody (SPM499)

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Immunohistochemistry-Paraffin: Dystrophin Antibody (SPM499) [NBP1-35784] - Human Skeletal Muscle

Product Details

Summary
Product Discontinued
View other related Dystrophin Primary Antibodies

Order Details


    • Catalog Number
      NBP1-35784
    • Availability
      Product Discontinued

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Dystrophin Antibody (SPM499) Summary

Immunogen
Synthetic peptide corresponding to C-terminus of human dystrophin.
Specificity
This product is specific for Dystrophin
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DMD
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50
Application Notes
IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mMcitrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Dystrophin Antibody (SPM499)

  • BMDDXS272
  • CMD3B
  • DXS142
  • DXS164
  • DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272
  • DXS206
  • DXS230
  • DXS239
  • DXS268
  • DXS269
  • DXS270
  • dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142
  • dystrophin

Background

Dystrophin is a member of the spectrin/alpha-actinin family of actin-binding, triple helix rod-containing proteins. It is absent or greatly reduced in individuals with the X-linked recessive Duchenne's muscular dystrophy disorder, as well as in mice with the mdx (murine muscular dystrophy) mutation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Dystrophin Products

Bioinformatics Tool for Dystrophin Antibody (NBP1-35784)

Discover related pathways, diseases and genes to Dystrophin Antibody (NBP1-35784). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Dystrophin Antibody (NBP1-35784)

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Pathways for Dystrophin Antibody (NBP1-35784)

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PTMs for Dystrophin Antibody (NBP1-35784)

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Research Areas for Dystrophin Antibody (NBP1-35784)

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Blogs on Dystrophin.

Could Laminin be Used to Treat Duchenne Muscular Dystrophy?
Duchenne muscular dystrophy (DMD) is a severe muscle wasting condition, causing disability and early death. There is currently no cure or adequate treatment for DMD, but pioneering research indicates that injection of a laminin protein may prevent (or...  Read full blog post.

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Bioinformatics

Gene Symbol DMD
Entrez