Dystrobrevin beta Antibody (3A12)

Images

 
Western Blot: Dystrobrevin beta Antibody (3A12) [NBP2-01798] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Dystrobrevin beta (Right lane) cDNA for 48 hrs and lysed. Equivalent ...read more
Immunocytochemistry/ Immunofluorescence: Dystrobrevin beta Antibody (3A12) [NBP2-01798] Staining of COS7 cells transiently transfected by pCMV6-ENTRY Dystrobrevin beta.
Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody (3A12) [NBP2-01798] - Staining of paraffin-embedded Human prostate tissue using anti-Dystrobrevin beta mouse monoclonal antibody.
Flow Cytometry: Dystrobrevin beta Antibody (3A12) [NBP2-01798] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-Dystrobrevin beta ...read more
Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody (3A12) [NBP2-01798] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-Dystrobrevin beta mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody (3A12) [NBP2-01798] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-Dystrobrevin beta mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody (3A12) [NBP2-01798] - Staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-Dystrobrevin beta mouse monoclonal antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Clone
3A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Dystrobrevin beta Antibody (3A12) Summary

Immunogen
Full length human recombinant protein of human DTNB(NP_899205) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
DTNB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Dystrobrevin beta Antibody (3A12)

  • beta-dystrobrevin
  • DTN-B
  • dystrobrevin beta
  • dystrobrevin, beta
  • MGC17163
  • MGC57126

Background

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DTNB
Entrez