Dynamin Antibody

Images

 
Western Blot: Dynamin Antibody [NB100-92029] - 1 (V768) pAb in extracts from PC12 cells.
Immunohistochemistry-Paraffin: Dynamin Antibody [NB100-92029] - Human tbrain tissue.
Western Blot: Dynamin Antibody [NB100-92029] - Analysis of Dynamin-1 (V768) antibody in extracts from mouse brain

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-92029
    • Availability
      Product Discontinued

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Dynamin Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 750-800 of Human Dynamin-1.
Clonality
Polyclonal
Host
Rabbit
Gene
DNM1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of Dynamin-1 (V768) pAb in extracts from PC12 cells.
Immunohistochemistry (IHC) analyzes of Dynamin-1 (V768) pAb in paraffin-embedded human tbrain tissue.
Theoretical MW
98 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Cross reacts with Human, Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Dynamin Antibody

  • DNM
  • DNM1
  • dynamin 1
  • Dynamin
  • dynamin-1
  • EC 3.6.5.5

Background

Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression in testis. Both Dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the Dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to Clathrin coated pits by SH3 domain interaction with Amphiphysin, a protein highly expressed in brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Dynamin Antibody (NB100-92029)

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Bioinformatics

Gene Symbol DNM1
Entrez